This pizza casserole is a delightful twist on the classic pizza. Combining all the flavors you love in a pizza but in a comforting casserole form, it's perfect for family dinners or gatherings. With layers of ground beef, pizza sauce, and topped with gooey mozzarella cheese, pepperoni, and fresh vegetables, this dish is sure to be a hit.
If you don't usually stock pizza sauce or pepperoni at home, you might need to pick these up at the supermarket. Pizza sauce can often be found in the pasta aisle, while pepperoni is typically located near the deli or in the refrigerated section. Fresh bell peppers, onions, and mushrooms are usually in the produce section.

Ingredients For Pizza Casserole Recipe
Ground beef: Provides a hearty base for the casserole, adding rich flavor and protein.
Pizza sauce: Adds the classic pizza flavor with a tangy tomato base.
Mozzarella cheese: Melts beautifully to create a gooey, cheesy topping.
Pepperoni: Adds a spicy, savory element to the dish.
Bell peppers: Adds a fresh, sweet crunch and vibrant color.
Onions: Provides a savory depth of flavor.
Mushrooms: Adds an earthy flavor and meaty texture.
Italian seasoning: A blend of herbs that enhances the overall flavor of the casserole.
Technique Tip for This Recipe
When browning the ground beef, make sure to break it up into small, even pieces to ensure it cooks evenly. For added flavor, consider seasoning the beef with a pinch of salt and pepper while it cooks. This will enhance the overall taste of the pizza casserole. Additionally, sauté the bell peppers, onions, and mushrooms in the same skillet after browning the beef. This will help to soften them and bring out their natural sweetness, adding more depth to your dish.
Suggested Side Dishes
Alternative Ingredients
ground beef - Substitute with ground turkey: Ground turkey is a leaner option and provides a similar texture and flavor.
pizza sauce - Substitute with marinara sauce: Marinara sauce has a similar tomato base and seasoning, making it a good alternative.
shredded mozzarella cheese - Substitute with shredded provolone cheese: Provolone melts well and has a mild flavor that complements pizza dishes.
pepperoni slices - Substitute with turkey pepperoni: Turkey pepperoni is a lower-fat option that still delivers the classic pepperoni taste.
chopped bell peppers - Substitute with chopped zucchini: Zucchini provides a similar texture and adds a mild, slightly sweet flavor.
chopped onions - Substitute with chopped shallots: Shallots offer a milder, sweeter taste compared to onions.
sliced mushrooms - Substitute with sliced zucchini: Zucchini can provide a similar texture and absorb flavors well.
italian seasoning - Substitute with herbes de Provence: Herbes de Provence contains a blend of herbs that can mimic the flavor profile of Italian seasoning.
Other Alternative Recipes Similar to This Dish
How To Store / Freeze This Casserole
Allow the pizza casserole to cool completely before storing. This helps prevent condensation, which can make the dish soggy.
Transfer the cooled casserole into an airtight container. If you don't have a container large enough, you can use a baking dish covered tightly with aluminum foil or plastic wrap.
Store the container in the refrigerator if you plan to eat the leftovers within 3-4 days. This keeps the ground beef and vegetables fresh and safe to eat.
For longer storage, consider freezing the casserole. Cut it into individual portions for easy reheating. Wrap each portion tightly in plastic wrap and then place them in a freezer-safe bag or container. This double wrapping helps prevent freezer burn.
Label the containers with the date of storage. This helps you keep track of how long the pizza casserole has been stored, ensuring you consume it within 2-3 months for optimal taste and texture.
When ready to reheat, if refrigerated, preheat your oven to 350°F (175°C). Place the casserole in an oven-safe dish and cover with aluminum foil. Heat for about 20-25 minutes or until warmed through.
If frozen, it's best to thaw the casserole in the refrigerator overnight before reheating. This ensures even heating and maintains the quality of the mozzarella cheese and pepperoni slices.
For a quicker option, you can reheat individual portions in the microwave. Place a portion on a microwave-safe plate, cover with a microwave-safe lid or another plate, and heat on medium power for 2-3 minutes, checking and stirring halfway through to ensure even heating.
To maintain the crispiness of the pepperoni slices and bell peppers, consider reheating in a toaster oven or under the broiler for the last few minutes. This adds a delightful texture to your reheated pizza casserole.
How To Reheat Leftovers
Oven Method:
- Preheat your oven to 350°F (175°C).
- Place the leftover pizza casserole in an oven-safe dish.
- Cover the dish with aluminum foil to prevent the cheese from drying out.
- Bake for 15-20 minutes, or until heated through. The cheese should be melted and bubbly again.
- Remove the foil for the last 5 minutes if you want a crispy top.
Microwave Method:
- Place a portion of the pizza casserole on a microwave-safe plate.
- Cover with a microwave-safe lid or another plate to retain moisture.
- Heat on medium power for 2-3 minutes, checking halfway through to ensure even heating.
- Let it sit for a minute before serving to allow the heat to distribute evenly.
Stovetop Method:
- Heat a non-stick skillet over medium-low heat.
- Add a small amount of olive oil or butter to the skillet.
- Place the pizza casserole in the skillet and cover with a lid.
- Heat for 5-7 minutes, stirring occasionally to prevent sticking and ensure even heating.
- Once heated through, serve immediately.
Air Fryer Method:
- Preheat your air fryer to 350°F (175°C).
- Place the pizza casserole in the air fryer basket, ensuring it’s spread out evenly.
- Heat for 5-7 minutes, checking halfway through to ensure it doesn’t burn.
- The cheese should be melted and slightly crispy when done.
Best Tools for This Recipe
Oven: Used to bake the casserole at the specified temperature until the cheese is melted and bubbly.
Large skillet: Used to brown the ground beef over medium heat.
Mixing bowl: Used to combine the cooked ground beef, pizza sauce, and Italian seasoning.
Baking dish: Used to spread the beef mixture and layer the toppings for baking.
Spatula: Used to stir and mix the ground beef and other ingredients.
Measuring cups: Used to measure out the pizza sauce, shredded mozzarella cheese, pepperoni slices, bell peppers, onions, and mushrooms.
Knife: Used to chop the bell peppers and onions, and slice the mushrooms.
Cutting board: Used as a surface for chopping the vegetables.
Oven mitts: Used to safely handle the hot baking dish when removing it from the oven.
How to Save Time on Making This Dish
Pre-cook ingredients: Brown the ground beef and chop the vegetables in advance to save time on assembly day.
Use pre-shredded cheese: Opt for pre-shredded mozzarella to cut down on prep time.
Ready-made sauce: Use store-bought pizza sauce instead of making your own.
Batch cooking: Double the recipe and freeze half for a quick meal later.
One-pan method: Cook the ground beef and vegetables in the same skillet to reduce cleanup time.

Pizza Casserole Recipe
Ingredients
Main Ingredients
- 1 lb Ground beef browned and drained
- 1 cup Pizza sauce
- 2 cups Mozzarella cheese shredded
- 1 cup Pepperoni slices
- 1 cup Bell peppers chopped
- 1 cup Onions chopped
- 1 cup Mushrooms sliced
- 1 teaspoon Italian seasoning
Instructions
- Preheat your oven to 375°F (190°C).
- In a large skillet, brown the ground beef over medium heat. Drain any excess fat.
- In a mixing bowl, combine the cooked ground beef, pizza sauce, and Italian seasoning.
- Spread the beef mixture evenly in a baking dish.
- Top with shredded mozzarella cheese, pepperoni slices, bell peppers, onions, and mushrooms.
- Bake in the preheated oven for 25-30 minutes, or until the cheese is melted and bubbly.
- Let cool for a few minutes before serving.
Nutritional Value
Keywords
Suggested Appetizers and Desserts for This Recipe
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